Tuesday, November 4, 2008

Searching the Literature Part 2: Syntheses

In Part 1, I looked at the base of the literature Pyramid, the original Studies. The next level is Syntheses According to Haynes(2001), Syntheses are based on:

*Rigorous searches for evidence

*Explicit scientific reviews of the studies uncovered in the search


*Systematic assembly of the evidence to provide as clear a signal about the effects of a healthcare intervention as the evidence will allow.


Syntheses are more rapidly useable than the entire universe of Studies. Systematic Reviews are a particularly useful type of Synthesis, which set out to answer a single clinical questions.


  • The Trip Database, is a filter for searching for Evidence Based Medicine(EBM), which conveniently breaks search results into categories, including Systematic Reviews.

  • The Cochrane Collaboration is the most well known publisher of Systematic Reviews, a non-profit group that reviews evidence, based in England. Their website includes abstracts of reviews and plain language summaries.

  • You can also search for the abstracts in PubMed, in the Clinical Queries section, under the Finding Systematic Reviews.

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